Abstract

VISO, Miguel et al. Adiponectina y su relación con obesidad, insulinorresistencia y síndrome metabólico en adultos de la cohorte cdc de canarias en Venezuela. Rev. Venez. Endocrinol. Metab. [online]. 2013, vol.11, n.2, pp.76-86. ISSN 1690-3110.

Objective: To relate serum adiponectin levels with nutritional status and insulin resistance (IR) in adults with and without metabolic syndrome (MS) cohort belonging to the CDC de Canarias en Venezuela. Methods: The sample included 62 people, Canaries and children living in Venezuela. Anthropometry, blood pressure determination, analysis of fasting serum glucose, HDL-cholesterol, triglycerides, insulin and adiponectin, were performed. Results: Serum levels of adiponectin were significantly lower in individuals with obesity (2.16 ± 0.51 vs 2.62 ± 0.42, p = 0.032) and subjects with MS (1.85 ± 0.46 vs 2.55 ± 0.43 p = 0.000), compared to respective control group. Pearson analysis showed an inverse correlation of adiponectin with age, diastolic blood pressure as well as indicators of insulin resistance (HOMA, index triglycerides, HDL-cholesterol and triglycerides). Conclusion: In the whole sample, the subjects showed low serum adiponectin, implying a high cardiovascular risk, which could be partially explained by the presence of obesity, MS, RI or related to older age that increases the risk of oxidative stress.

Keywords : Adiponectin; insulin resistance; metabolic syndrome; nutritional; cardiovascular risk; Canary Islands.

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