Resumo

LIMA-MARTINEZ, Marcos M  e  GRUPO DE ENDOCRINOLOGIA MERIDA (ENDO-MER) et al. Manejo de pacientes con Síndrome de Cushing. Rev. Venez. Endocrinol. Metab. [online]. 2013, vol.11, n.3, pp.147-156. ISSN 1690-3110.

Chronic glucocorticoid excess is accompanied by a wide range of signs and symptoms known as Cushing’s syndrome. This condition most commonly arises from iatrogenic causes when glucocorticoids have been used as anti-inflammatory treatment for a long time. The pathogenetic mechanism of endogenous Cushing’s syndrome can be divided into ACTH dependent and ACTH independent. Despite major advances in diagnosis and therapy, Cushing’s syndrome is frequently a challenge for the clinician. In this paper, based on levels of scientific evidence and clinical experience in the Unit of Endocrinology, IAHULA, we present the protocol for the management of Cushing’s syndrome, which includes: diagnostic criteria, clinical management and treatment of this condition.

Palavras-chave : Cushing’s syndrome; cortisol; ACTH; pituitary.

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