Resumen

FERMIN, Melissa et al. Lipid profile in patients with polycystic ovary syndrome. Rev. Venez. Endocrinol. Metab. [online]. 2016, vol.14, n.3, pp.187-195. ISSN 1690-3110.

Objective: To analyze in patients with polycystic ovary syndrome (PCOS), abnormal lipid metabolism and its correlation with body mass index and insulin resistance. Methods: Observational, descriptive study of 30 patients with PCOS, who met the inclusion criteria between March and September 2013. Lipid profile was evaluated and correlated with body mass index (BMI), waist circumference (WC) and HOMA-IR, using the Cramer V coefficient. Results: The 36.67% (11/30 patients) had total cholesterol (TC)> 200 mg/dL; 86.67% (26/30 patients) HDL-C <50 mg/dL; 63.33% (19/30 patients) LDL-C >130 mg/dL and 73.33% (22/30 patients) triglycerides (TG) >150 mg/dL. The 93.33% (28/30 patients) showed abnormalities at least one factor lipid profile. We observed a low correlation between BMI and CT (0.20), BMI and HDL-C of 0.48 (moderate correlation) and BMI and TG 0.12 (very low correlation). The relationship between lipid profile and WC demonstrated a low correlation between WC and CT (0.25), WC and HDL-C 0.45 (moderate correlation), and WC and TG 0.23 (low correlation). The correlations between HOMA-IR and lipid profile showed a moderate correlation between HOMA-IR and CT (0.52), HOMA-IR and HDL-C of -0.34 (low inverse correlation), and HOMA-IR and TG 0,30 (low correlation). Conclusion: Dyslipidemia is common in patients with PCOS. The most frequent alterations were decreased HDL cholesterol (87.10%) and elevated TG (74.19%), which are cardiovascular risk factors in women.

Palabras clave : Polycystic ovary syndrome; dyslipidemia; lipid profile.

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