Abstract

CONTRERAS, Andrea; DURAN, Ana R; SIBRIAN, Bethelgeuse  and  MENDEZ, María V. Resistance to Fluorquinolones in Pseudomona aeruginosa and Staphiloccus aureus isolated from soft tissue in patients with Diabetes Mellitus, Aragua state. Comunidad y Salud [online]. 2011, vol.9, n.2, pp.44-53. ISSN 1690-3293.

Pseudomonas aeruginosa and Staphylococcus aureus are microorganisms involved in various infectious diseases in patients diagnosed with Diabetes Mellitus. They have high resistance to certain antibiotics. The aim of the study was to evaluate the resistance to fluoroquinolones in Pseudomonas aeruginosa and Staphylococcus aureus isolated from soft tissue in patients with Diabetes Mellitus in the Regional Service Center Podiatry (CARPO) Aragua State. The study was descriptive and cross-section. The methodological approach was based on the use of bacterial cultures, use of identification techniques and the Kirby Bauer method to evaluate the resistance of both organisms to fluoroquinolones. 150 samples were analized, 67 were positive for microorganisms under study. In this study, Pseudomonas aeruginosa was the organism isolated mainly (33.8%), while Staphylococcus aureus was the most frequent grampositivecocci (13.4%). A high resistance to fluorquinolones was found. Pseudomonas aeruginosa showed 95,83% and S. aureus 89.47%. The epidemiological factors and infection with resistant strains showed no statistical association. By contrast, prior treatment with fluoroquinolones and the degree of injury were found to have a relation with the organism isolated (p <0.05), indicating that P. aeruginosa and S. aureus are involved in serious injury in diabetic patients.

Keywords : Pseudomonas aeruginosa; Staphylococcus aureus; resistance to fluoroquinolones; Diabetes Mellitus.

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