Resumen

BASTIDAS BELTRAN, Danny; FIGUEROA ACOSTA, Luisa; PEREZ PINTO, Enrique  y  MOLINA PICON DE FERNANDEZ, Darjaniva. Status of resistance to organo-synthetic insecticides by an Aedes aegypti strain from Coro, Falcon state, Venezuela. Bol Mal Salud Amb [online]. 2015, vol.55, n.2, pp.173-183. ISSN 1690-4648.

Aedes aegypti is one of the most studied species in public health as the primary vector in humans the dengue, chicunguya, zyca virus and yellow fever. Response to organophosphorus insecticides malathion, fenitrothion, methyl-pirimiphos and carbamate propoxur was evaluated and the pyrethroid lambda-field strain called Coro, made up of a pool of material (immature) collected in neighborhoods with high casuistry of dengue Coro located in Miranda municipality, Falcón state, Venezuela; compared with the susceptible Rockfeller. Bioassays in insecticide-treated bottles were performed according to the method of the CDC and also the mechanisms of resistance in vitro were identified by biochemical tests. The resistant strain was evaluated to malathion (45 min), fenitrothion (75 min) methyl-pirimiphos (75 min) compared to the susceptible strain with 30, 45 and 45 min respectively, with mortality rates of 89 time threshold, 2% malathion, fenitrothion 55.7%, 56.6%, pirimiphos-methyl. Susceptibility to propoxur carbamate and pyrethroid lambda was found. As for the high values for biochemical tests esterases alpha (α) and beta (β) with statistically significant differences (P< 0.05) compared with the susceptible strain were found. Inhibited aceltilcholinesterase (Achei) despite significant differences with the Rockefeller strain values are below the same acetylcholinesterase. Falcon resistance to organophosphate insecticides strain appears to be associated with increased alpha esterases (α) and beta (β). The results represent a valuable contribution to monitor the resistance of Ae. aegypti locally within a program of integrated vector management.

Palabras clave : esterases; acetylcholinesterase; organophosphate; insecticide resistance.

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