Abstract

MIER ARAUJO, Jorge Oswaldo; MIER JIMENEZ, Jorge Alberto; DELGADO VEGA, Martha Verónica  and  ALDAZ VALLEJO, Freddy Alexander. We are Surgeons for children (Infant-us): result of the use of Senosides as a stimulant laxative, in the intestinal rehabilitation program. Revista InveCom [online]. 2025, vol.5, n.1, e501051.  Epub Dec 05, 2024. ISSN 2739-0063.  https://doi.org/10.5281/zenodo.11388213.

Sennosides, which are specifically extracted from the pericarp of cassia acutifolia (also known as Senna of Alexandria), are active glycoside compounds that consist of a complex bonding of sugars with the anthraquinone derivative rhein. These compounds have made it possible to standardize senna extracts, a plant recognized since ancient times for its effectiveness as a laxative, and which is characterized by lacking unwanted side effects. Sennosides A and B are substances that act as laxatives by increasing the activity of the muscles of the intestine by stimulating the nerve endings present in the intestinal wall. When this medication is used, the movement of intestinal contents is accelerated, leading to relief from constipation by facilitating faster transit along the intestinal tract. It takes 6 to 10 hours for this medication to work. This study was planned to analyze and determine the effectiveness of sensorosides in treating chronic functional constipation in pediatric patients. The main objective of this study is to obtain the results of the use of sinosides as a stimulant laxative in pediatric patients. The methodological strategies used was the study of the medical records obtained from Infant-us since 2017 where we obtained the relevant data and used the Excel program to process and analyze the results. A successful response of 85% to the use of sinuses as a stimulant laxative was demonstrated in patients in the "intestinal rehabilitation" program.

Keywords : sennosides; chronic functional constipation; laxative.

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