Resumo

CASTILLO ESPEJO, Kevin; GARCIA DE BARRIOLA, Victoria; ROCHA, Miguel  e  TEJADA, Augusto. Magnetic resonance imaging and anatomo-pathological findings in mastectomy specimens and axillary lymph nodes in breast cancer patients. Rev Cien CMDLT [online]. 2023, vol.17, n.1, e-231406.  Epub 28-Mar-2025. ISSN 2790-8305.  https://doi.org/10.55361/cmdlt.v17i1.406.

Introduction: Breast cancer is the most common type of cancer in women. In 2020, 685.000 deaths were registered. Survival and probability of recurrence depends on stage at diagnosis. The main objective of this investigation was to evaluate the MRI and pathological findings in breast and axillary lymph nodes specimens at Centro Médico Docente La Trinidad during the 2015- 2023 period. This was an observational, retrospective and descriptive study. The universe consisted of 215 breast cancer patients. The sample obtained was of 18 cases after applying the inclusion and exclusion criteria. Breast and axillary lymph node specimens from the patients with MRI and pathological studies were included. The results showed an average age of 58.17 ± 10.99 years. Tumor location had no difference in the laterality of the breast. The upper-outer quadrant predominated (n=10, 55.56%). The absence of multifocality (n=12, 66.67%) and the apparent diffusion coefficient (ADC) less than 1 (n=14, 77.78%) stood out. Infiltrating ductal carcinoma was the main diagnosis. Statistical significance was not enough to establish dependence between tumor size, lymphovascular invasion, nuclear grade, molecular subtype, multifocality and ADC with the presence of metastasis to axillary lymph nodes (ALN). On the contrary, there was a relationship between high Ki67 expression and the molecular subtypes, HER-2- overexpressing and triple-negative (p-value 0.005). We concluded in the need for multicenter studies with larger samples in order to establish dependency relationships between the variables of interest.

Palavras-chave : Breast cancer; Magnetic resonance; Axillary lymph nodes; Metastasis.

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