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Gen
Print version ISSN 0016-3503On-line version ISSN 2477-975X

 

Table of contents
Gen vol.61 no.2 Caracas June 2007

 Carta a la Edición
  
 
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 Editorial
  
 ·  ¿Es posible estudiar el intestino delgado por endoscopia?
Sánchez Quijano, Alvaro

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 ·  Polipos, lesiones planas digestivas superiores y cromoscopia
Bracho Mosquera, Víctor

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 Artículos Originales
  
 ·  Rendimiento diagnóstico de la cápsula endoscópica y enteroscopia doble balón en pacientes con hemorragia digestiva oscura
Narváez, M; Landaeta, J; Rodríguez, M; Mutti, L; Paredes, R; Guzmán, M; Sandoval, C; Vásquez, F; Rojas, B; Khassale, M; Acevedo, Y; Castro, J; Veitía, G

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 ·  Cápsula endoscópica y enteroscopia doble balón en pacientes con patología del intestino delgado
Landaeta, J; Rodríguez, M; Paredes, R; Mutti, L; Narváez, M; Rojas, B; Khassale, M; Hernández, I; Castro, J; Sandoval, C; Vásquez, F; Guzmán, M; Veitía, G

        · abstract in English | Spanish     · text in Spanish
  
 ·  Introduction and Aims: Combined treatment with pegylated interferon and lamivudine can constitute a suitable alternative in order to obtain seroconversion in pediatric patients with virus B chronic infection. The aim of the present study was to evaluate the response of pediatric patients with chronic virus B infection given by the lost of Age VHB and DNA VHB, and the appearance of antibodies against Age VHB and normalization of aminotranferases in patients treated with pegylated interferon alpha 2a in combination with lamivudine. Patients and Methods: Pediatric patients with chronic infection by virus B were included, with positive HBe Ag, anti- HBe Ab-, HBV DNA positive, elevation of aminotranferases for more than 6 months These patients received treatment with pegylated interferon alpha 2a and lamivudine 4 mgs/kg/day for 52 weeks. Results: The transmission routes were vertical in 2 patients, transfusional in 7and 1 unknown. PatientÊs mean age was 10,3+ 3,47 years, with an average time of exposure to virus B of 5,2+3,93 years. The average of aminotranferases at the beginning of treatment was AST 112,3+46,3 and ALT 127,8 + 44. Twelve weeks following treatment AST levels were 33,3+12,14 and ALT 35,5+ 13,51.The histological findings were: 2 patients had moderate inflammatory activity, 8 mild activity , 2 developed moderate fibrosis and 8 mild fibrosis. Only 1 patient developed anemia and leucopenia that did not require the suspension of treatment. Ten (10) patients (100%) developed fever, 8 (80%) migraine during the 4 first weeks of treatment; they remained asymptomatic during the 48 remaining weeks. The 10 patients had normal aminotranferases at 12 weeks following treatment. Two (2) (20%) of the patients presented loss of Ags VHB and Ac positive Ags VHB 12 weeks post treatment. Of 10 patients 4 (40%) had seroconversion (Age VHB, negative DNA VHB and Ab positive Age VHB) by week 52 of treatment and 12 weeks post treatment. Conclusion: Combined treatment with pegylated interferon and lamivudine constitute an effective and safe therapeutic option for pediatric patients with chronic infection by virus B.
Pestana, Elena; León, Keira; Pierre, Reinaldo; Olza, María Teresa; Hassan, Isaac

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 ·  Biliary complications are present in 13% to 35% of patients who undergo liver transplantation. ERCP has been used as the endoscopic method to solve these problems. Objective: To show Venezuela's  experience, using endoscopic therapy in biliary complications post orthotopic liver transplantation (OLT) including anastomotic stricture, fistula and anatomic distortion. Patients and methods: Since 2003, (16) orthotopic liver transplantations have been performed, 7 patients (43,75%) had biliary complications. ERCP was performed in all patients. Results: 3 of them presented biliary fistulas, 1 supra- anastomotic stricture, 1 anastomotic stricture and 2 cases with biliary anatomic distortion. Endoscopic sphincterotomy with biliary stenting was performed in 5 patients, sphincterotomy with balloon dilation and stenting in 1 patient and only sphincterotomy in 1 patient. There were no complications for the procedure and all the patients had good clinical outcome. Conclusions: Early diagnosis and early endoscopic therapy through ERCP are the most important tools to solve biliary complications following liver transplantation.
Rojas, Beatriz; Rodríguez, María; Carreta, Mauro; Malavé, Hermógenes; Pérez, Iraima; Naranjo, Laura; Pestana, Elena; Oviedo, Franklin; Carucci, Pascual; Castro, Julio; Ríos, Antonio; Bazalo, Miguel; Socorro, María; Urdaneta, Clotty; Landaeta, Jorge; Rivas-Vetencourt, Pedro

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 Reportes Preliminares
  
 ·  Pólipos de estómago y duodeno: Una revisión de 1 año de experiencia en un centro de referencia
Sihues, Edgar; Añez, Marianela; Lizarzábal, Maribel; Rangel, Rosa; Fernández, José; Romero, Gisela; Latuff, Zully; Serrano, Ana

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 ·  Absceso hepático amibiano en la consulta de adultos en el servicio de Gastroenterología Dr. Alí Rivas, Hospital Jesús Yerena Lídice, entre los años 2000 y Mayo 2006
Ortiz, Andres; Suarez, Dorys; Fernandez, Gustavo; Cruz, María; Clavo, Mary; Dib, Jacobo

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 ·  Estudio experimental de los efectos producidos por el bromuro de pinaverio y el tegaserod sobre el aparato gastrointestinal en animales de experimentación
Requena, Daniel; Salinas, Pedro; Silva, Carlos; Valero, Raimir; Ortega, Ligia; Gómez, Virginia; Gutiérrez, José

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 Casos Clínicos
  
 ·  Teratoma rectal: Reporte de un caso
Dib, Jacobo Jr; Delgado, María; Cruz, María; Ortiz, Andres; Clavo, Mary; Suarez, Dorys; Fernandez, Guatavo

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 ·  Tumor estromal gástrico gigante
Gil, G; Valero, E; Walczuch, P; Suàrez, M; Gumina, Cono

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 ·  Atrofia lobar hepática: A propósito de un caso
Delgado Navas, María Gabriela; Rodríguez, Ritelix; Dagher, Lucy

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 ·  Prostaglandina tisular y niveles séricos del factor de necrosis tumoral alfa (TNF-α) en un modelo experimental de rectocolitis aguda en ratas
Sorentino, Rebeca; Canaroso, Maria Alejandra; Mendible, Francis; Méndez, Mariana; Carvajal, Sol; Gutiérrez, José

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 ·  Tricobezoar gástrico: Presentación de un caso
Norlan de la Cruz, Alfonso; de Jesús, Zuleyma Carolina; Noa Pedroso, Guillermo; Casanova Rivero, Alberto

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 Artículos de Revisión
  
 ·  La gastroenterología venezolana en sus inicios: Recuento de la historia de la revista gen sus diez primeros años (III parte)
Poleo, José Ramón

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 ·  Trasplante hepático en Venezuela
Vetencourt Rivas, Pedro A; Mauro, Carretta

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 Revisión de Revistas
  
 ·  Terapia intravenosa con IPP antes de endoscopia secundaria a hemorragia digestiva superior


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 Carta al Editor
  
 
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 Fe de Errata
  
 
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